Hepatocytes metabolize energy-rich cytoplasmic lipid droplets (LDs) within the lysosome-directed strategy of autophagy. An organelle-selective type of this course of (macrolipophagy) leads to the engulfment of LDs inside double-membrane delimited buildings (autophagosomes) earlier than lysosomal fusion. Whether or not that is an unique autophagic mechanism utilized by hepatocytes to catabolize LDs is unclear. Additionally it is unknown…
